Micro-Iontophoresis High Voltage Six Channel Current Generator (Dagan)

The Dagan 6400Advanced is a system, which consists of six fully programmable High Voltage constant current generators for use with single or multi barrel microelectrodes. Without the need of any batteries, precise iontophoretic drug ejection is accomplished by passing controlled constant currents through the drug carrying electrodes.



  • High Compliance Voltage (± 135 V)
  • Electrode Resistance Test
  • Programmable Timer
  • 7th Sum Channel
  • ± 1000 nA range
  • Electrode Blocking indicators


Current Monitoring

The 6400Advanced measures the ACTUAL current passing through the electrode barrel (rather than the expected current), and displays the current in nA's on the digital read out monitor.

The output current can also be monitor via a back panel BNC. Each channel also has a monitor LED that alerts the operator of electrode "BLOCKING" (microelectrode failure to pass current).


Time Programming

The 6400Advanced includes the versatile AUTO SEQUENCE PULSER which switches any or all channels into the eject mode sequentially for the duration of its independently preset drug ejection time with a common interval time between channels. Each channel can also be independently operated via the front panel controls or an external digital control. Combinations of these are also possible.



Current Source Parameters

Compliance voltage   270 V peak to peak

Current Range
     Eject:  Two Ranges;  ± 100 nA,  and  ± 1000 nA
     Retain:    ± 100nA

Maximum Electrode Resistance
     Output Current  100 nA,    1.35 GΩ
     Output Current  1000nA,    1.35 MΩ



Current Mode    Displays the Actual Measured Current of the selected Channel.  ± 1000 nA range.

Z Test Mode     Displays the Actual Measured Electrode Resistance of the selected Channel. 1999 MΩ range.

Sum Channel    7th Channel, supplying a current equal in magnitude but opposite in sign to the sum of the currents in the six channels (1000 nA range).


Current Programming

Front Panel

Eject    Selectable Positive or Negative 100 nA / 1000 nA one-turn control.  Scaled by Range switch.

Retain    Selectable Positive or Negative 100nA one-turn control.

100 nA/V, rear panel inputs. Maximum input 10 V (1000 nA command).



Cabinet    7.0" high, 19.0" wide, 10.0" deep. (17.7 × 48.3 × 25 cm)

Probe       Pencil Probe; 0.5" Diameter, 4" Long , Ten Foot Cable


Power Requirements

100 to 115 or 200 to 230 V AC (selectable with internal switch), 50 or 60 Hz, 20 W.


Delivery subject to the reservation of limited availability from the manufacturer.